Sugar on the Brain & Belly!
Monday, 10 June 2019
This week is Diabetes Awareness Week, and so is the topic of my blog this week as well as the focus of my fourth and final pillar in the "pillars of health" Functional Day Retreat series on 10th July.
Compelling and staggering statistics about the projected state of our health as a nation makes for some grim reading………..
Since 1996 the number of people diagnosed with diabetes has increased from 1.4 million to 2.6 million. By 2025 it is estimated that over four million people will have diabetes and one million, will have a diagnosis of dementia.
So what are we doing wrong? - I propose we need to consider that there can be a number of contributing factors to dis-ease (moving away from ease) and that the “treatment” for “disease” with a single drug, the model of monotherapy is too linear for the explosion of chronic conditions that is crippling our NHS system.
A Functional Medicine approach offers a framework that addresses the many possible underlying causes of these conditions, dementia being just one.
A growing body of research indicates that Dementia is closely linked to poor blood sugar control (the step before diabetes) and diabetes. Searching on PubMed today (8th June 2019) bought up 1471 published studies linking dementia & blood sugar.
Dr. Dale Bredesen, an internationally recognized expert on neurodegenerative disease, states that Alzheimers and dementia is a multifactor condition and that Amyloid-beta is not the main problem, but rather the brain’s response to one (or more than one) insults (1). He has identified several types of AD, each with unique causes (4, 5):
So let us take a closer look at the area of blood sugar control, insulin resistance and diabetes, which links with type 1.5 and 2 in his model.
Insulin resistance and blood sugar control
Do you feel exhausted all the time? Are you overweight? Or just starting to gain weight around your midriff? Do have serious blood sugar imbalances, or have elevated cholesterol, blood pressure, and triglyceride levels? Even if just one or two of these points resonate with you, it is highly likely that you need to address your blood sugar and insulin levels.
Your body’s preferred fuel source is glucose, which it needs for energy. Glucose is released from your food and then is carried in the blood to the cells where it’s converted into energy. For the glucose to be able to enter the cells, it requires a transport mechanism. This is where insulin comes into play.
Insulin is a hormone secreted by the pancreas and its purpose is to “unlock” the cells and facilitate the transport of glucose into the cells where it can be converted into energy. As we eat a meal, our blood sugar levels rise. However, carbohydrate-based foods raise blood sugar levels significantly more than protein or fat, and the type of carbohydrate we eat has even more significance. Overly-processed carbohydrate foods such as cakes, biscuits, pizza, white bread and pasta, together with fizzy drinks and alcohol cause a far more rapid rise in blood sugar levels. Wholegrain breads, pasta, rice, fruits and vegetables provide a more slow and sustained release, in the main because of the fibre content still present.
If the body is continuously exposed to high levels of blood sugar from eating these overly-processed types of carbohydrates, then the pancreas has to compensate by secreting excessive levels of insulin to be able to move all this excess sugar/glucose out of the bloodstream and into the cells. The body can cope with this state of excess for a period of time, but certainly not indefinitely, and if continued, the insulin receptors on the cells start to become quite literally deaf to the call of this extra insulin, and the “unlocking” process of allowing sugar into the cells to form energy becomes blunted. This is a condition called insulin resistance, and eventually, if left unchecked, will lead to full-blown diabetes.
Insulin resistance is part of a health spectrum, also referred to as metabolic syndrome, that includes many all-too-common health conditions:
How blood sugar dysregulation harms brain function
We’ve established that glucose, a form of sugar, is the primary source of energy for every cell in the body. Because the brain is so rich in nerve cells, or neurons, it is the most energy-demanding organ, using one-half of all the sugar energy in the body.
Brain functions such as thinking, memory, and learning are closely linked to glucose levels and how efficiently the brain uses this fuel source. If there isn’t enough glucose in the brain, for example, neurotransmitters, the brain’s chemical messengers, are not produced and communication between neurons breaks down. In addition, hypoglycemia, a common complication of diabetes caused by low glucose levels in the blood, can lead to loss of energy for brain function and is linked to poor attention and cognitive function.
Although the brain needs glucose, too much of this energy source can be a bad thing. A 2009 study conducted by a team of scientists at the University of Montreal and Boston College, linked excess glucose consumption to memory and cognitive deficiencies.
The effects of glucose and other forms of sugar on the brain may be the most profound in diabetes - either type 1 or type 2. High blood glucose levels can affect the brain’s functional connectivity, which links brain regions that share functional properties, and brain matter. It can cause the brain to atrophy or shrink. And it can lead to small-vessel disease, which restricts blood flow in the brain, causing cognitive difficulties and, if severe enough, spurring the development of vascular dementia.
Optimize glycemic control to protect health
A Functional Medicine approach that addresses diet, physical activity, and gut health can help optimize glycemic control and prevent the onset of dis-ease associated with diabetes and insulin resistance.
My top diet tips are:
The broader message is that by removing the “insults” and optimizing health we have a far better chance for living a long and healthy life!
If any of this has resonated with you, please consider booking a spot at my upcoming Functional Day Retreat: Healthy For Life! - you will leave informed and with a practical roadmap to follow - for life!
In health, Tanya x